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Overview of Webinars
Thursday, July 13th
11:00 AM SGT
Thursday, July 20th
11:00 AM SGT
Thursday, July 27th
11:00 AM SGT
How to Solvent Switch Successfully
Robust Method Development and Optimization for Characterizing Biotherapeutics
LC Pressure 101
Speaker: Genevieve Hodson - Manager of Technical Support, Phenomenex
Speaker: Namrata Saxena - Technical Manager , Phenomenex
Speaker: Genevieve Hodson - Manager of Technical Support, Phenomenex
Key Learning Points:
- What is solvent miscibility and why is it important to understand.
- Why it is necessary to properly solvent switch a column and what can happen if it is not done correctly.
- A general procedure to switch an LC column from one solvent to another.
- Tips to keep in mind when performing solvent switches.
- What are common examples of solvent switching to look out for.
Key Learning Points:
- Understand the methodologies and approaches of developing characterization methods for biotherapeutics
- Identify key method parameters that effect method robustness
- Establish control strategies that ensures robust performance and high quality data
Key Learning Points:
- Understand how backpressure is measured in LC instruments.
- Why backpressure is important to measure in the system and column.
- How different dimensions of column hardware and system tubing can influence overall backpressure.
- How different mobile phases and flow rates can impact backpressures.
- What different types of sample matrix can do to backpressure and how to mitigate.
- Tips to troubleshoot to root cause of backpressure issues.
Who Should Attend:
- Any LC users looking to utilize different modes of separation and are required to switch a column that is shipped with an immiscible solvent to the one method requires
Who Should Attend:
- Any method development scientists or anyone involved in optimizing/modernizing methods
Who Should Attend:
- Any LC users who are looking to understand the factors that can impact a systems backpressure and how to mitigate potential backpressure problems.
Meet Our Speakers
Genevieve Hodson
Manager of Technical Support, Phenomenex
Genevieve graduated from the University of Texas with a BS in Chemistry located in her home town of Austin Texas. She spent 2 years of her undergraduate performing research in an Organic Chemistry Lab synthesizing intermediates. Out of school she spent 4 years as an Analytical Chemist in the QC and R&D Department of Cerilliant (a Sigma Millipore Company). There she worked with many analytical instruments but became an expert at LC by performing purity analysis, customer specific methods, validations, qc testing and stability studies on a wide range of small molecules including pharmaceuticals, pesticides, explosives and illegal substances.
From there she moved to Los Angeles California where she worked at Johnson and Johnson and then a small dietary supplement company. After Genevieve spent a year living abroad in Israel raising her first son, she moved back to LA where she got hired as a Technical Specialist at Phenomenex. At Phenomenex she enjoys continuing to learn about chromatography every day through helping customer with all their chromatography needs!
Namrata Saxena
Technical Manager, Phenomenex
Namrata Saxena is a Technical Manager - Asia/Pacific” with Phenomenex and is based in Sydney, Australia. She has a post graduate degree with a specialization in Analytical Chemistry, with extensive experience in the Liquid chromatography domain, and her current focus is in Omics and Biologics field.
Before joining Phenomenex she had worked as “Product Specialist” and spent several years in column chemistry, column manufacturing and method development in the application and manufacturing labs of Bischoff Chromatography, Germany.
In her current role, she provides product selection, method development, training and troubleshooting support to customers as well as Phenomenex Sales Consultants globally
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