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Method Development and Optimization of Native RPLC-HRMS Characterization of ADCs using Biozen Native RP Columns

During this presentation, you will:

An RPLC-HRMS method development approach for rapid, comprehensive DAR analysis, including positional isomers, under native conditions.
Sorbent polarity and hydrophobicity effects on retention and selectivity of individual DAR species.
Optimized chromatographic separation and MS identification of all DAR species, including positional isomers, of several ADCs.

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