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Simple Drug Testing Solutions for Complex Samples

During this presentation we will review:
  • Advantages of the biphenyl LC column chemistry for drug analysis
  • Using phospholipid removal to produce cleaner samples and improve drug quantitation
  • Implementing mixed-mode SPE with in-well room temperature hydrolysis to extract “designer” benzodiazepines and conjugated metabolites from urine using a streamlined workflow
  • Strategies for removing endogenous constituents and collection device components from oral fluid samples prior to LC-MS/MS analysis using microelution SPE
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